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AH EXPERIMENTAL STUDY OF THE EFFECT OF FLUORIDE COMPOUNDS ON THE GROWTH OF STREPTOCOCCUS MUTANS

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Abstract

°á·Ð
¿©·¯ ³óµµ Áï 0, 75, 150, 300, 600 ppmF ³óµµÀÇ NaF ¿Í SnF2°¡ ¿ì½Ä¼º¼¼
±ÕÀÎ Streptococcus mutansÀÇ Áõ½Ä¿¡ ¹ÌÄ¡´Â È¿°ú¸¦ ºñ±³Çϱâ À§ÇÏ¿© ½ÃÇàÇÑ º» ¿¬±¸ÀÇ °á
°ú´Â ´ÙÀ½°ú °°´Ù.
1. NaF ¿¡ ÀÇÇÑ Streptococcus mutansÀÇ Áõ½Ä¾ïÁ¦È¿°ú´Â 75 ppmF ³óµµ¿¡¼­´Â °ÅÀÇ ¾ø¾ú
°í, 150 ppmF ³óµµ¿¡¼­´Â Áõ½Ä¼Óµµ°¡ ´À·ÁÁ³À¸¸ç, 300°ú 600 ppmF ³óµµ¿¡¼­´Â Áï½Ã Áõ½Ä
ÀÌ ÁߴܵǾú´Ù.
2. SnF2¿¡ ÀÇÇÑ Áõ½Ä¾ïÁ¦È¿°ú´Â 75 ppmF ³óµµ¿¡¼­ Áõ½Ä¼Óµµ°¡ ´À·ÁÁ³À¸¸ç,
150°ú 300 ppmF ³óµµ¿¡¼­´Â Ãʱ⿡ »ì±ÕÀÛ¿ëÀÌ º¸ÀÌ´Ù°¡ ÁߴܵǾú°í, 600 ppmF ³óµµ¿¡¼­
´Â °ÅÀÇ ¿ÏÀüÇÑ »ì±ÕÀÛ¿ëÀÌ ³ªÅ¸³µ´Ù.
3. °°Àº ³óµµ¿¡¼­ÀÇ Streptococcus mutansÀÇ Áõ½Ä¾ïÁ¦È¿°ú´Â SnF2°¡ NaF
º¸´Ù Å©°Ô³ªÅ¸³µ´Ù.
4. 600 ppmF ³óµµ¿¡¼­ pH¿¡ µû¸¥ Áõ½Ä¾ïÁ¦È¿°ú´Â pH°¡ ´õ ³·Àº »óÅ¿¡¼­ ´õ Å©°Ô ³ªÅ¸
³µ´Ù.
#ÃÊ·Ï#
The purpose of this study was to compare the growth-inhibiting effect of sodium
fluoride and stannous fluoride on a cariogenic strain of Streptococcus mutans exposed to
the different concentration of SnF2 and NaF.
The result were as follows:
1. The growth rate of the Streptococcus mutans was unaffected by 75 ppmF, slowed
by 150 ppmF, and immediately arrested by 300 or 600 ppmF where increments of NaF
were added to actively growing 12-hour broth culture.
2. SnF2 slowed the growth rate at 75 ppmF, was to bactericidal initially
at 150 and 300 ppmF, and was to totally bactercidal at 600 ppmF.
3. SnF2 has been shown to be more effective than NaF in inhibiting the
growth activity of Streptococcus mutans.
4. The inhibitory effect of fluoride compounds on the growth of Streptococcus mutans
was increased in the decreased pH at concentration of 600 ppmF.

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